APLS Apellis Pharmaceuticals Inc

$25.24

*Only the 1D chart reflects 15-min delayed quotes during market hours. Other timeframes update after market close.

Reporting for fiscal period ending
Expected on
Report Time: Unknown Release Time
The Whisper Number
Consensus Estimate:
Revenue Estimate:

Latest Earnings Insight

Updated On 12/31/2025

About Apellis Pharmaceuticals Inc

Apellis Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on the development of therapeutic compounds through inhibition of the complement system for autoimmune and inflammatory diseases. The company is headquartered in Waltham, Massachusetts.

Website: https://apellis.com

Sector
LIFE SCIENCES
Industry
PHARMACEUTICAL PREPARATIONS
Exchange
NASDAQ
Country
USA
Currency
USD
Fiscal Year End
December
CIK
1492422
Address
6400 WESTWIND WAY, SUITE A, CRESTWOOD, KY, US
Valuation
Market Cap
$2.28B
P/E Ratio
nan
PEG Ratio
nan
Price to Book
10.00
Performance
EPS
$-1.60
Dividend Yield
Profit Margin
-25.30%
ROE
-93.50%
Technicals
50D MA
$24.37
200D MA
$30.88
52W High
$50.98
52W Low
$17.48
Fundamentals
Shares Outstanding
126M
Target Price
$42.35
Beta
0.84

APLS EPS Estimates vs Actual

Estimated
Actual

APLS News & Sentiment

Dec 30, 2025 • MarketBeat NEUTRAL
Simplify Asset Management Inc. Buys New Stake in Apellis Pharmaceuticals, Inc. $APLS
Simplify Asset Management Inc. has acquired a new position in Apellis Pharmaceuticals, Inc. (NASDAQ:APLS), purchasing 106,888 shares valued at approximately $2.42 million during the third quarter. This move comes as Apellis Pharmaceuticals outperformed earnings expectations, reporting an EPS of $1.67 against an estimated $1.03 and revenues of $458.6 million, a 133% increase year-over-year. The company currently has an average "Hold" rating from analysts with a price target of $33.94, despite recent insider share sales.
Dec 30, 2025 • Stock Traders Daily NEUTRAL
Understanding Momentum Shifts in (APLS)
This article analyzes momentum shifts for Apellis Pharmaceuticals Inc. (NASDAQ: APLS) using AI models, highlighting a mixed sentiment alignment and a mid-channel oscillation pattern. It presents three distinct trading strategies—Position Trading, Momentum Breakout, and Risk Hedging—tailored for different risk profiles and holding periods, alongside multi-timeframe signal analysis indicating varying support and resistance levels. The report also details an exceptional short setup targeting a 20.0% downside with minimal risk.
Dec 27, 2025 • MarketBeat NEUTRAL
Highland Capital Management LLC Takes Position in Apellis Pharmaceuticals, Inc. $APLS
Highland Capital Management LLC has acquired a new position in Apellis Pharmaceuticals, Inc. (NASDAQ:APLS), purchasing over 50,000 shares valued at approximately $1.135 million. This move comes despite recent insider selling by the CFO and General Counsel, totaling over $1.3 million. Apellis Pharmaceuticals recently surpassed quarterly earnings and revenue estimates, yet analysts maintain a consensus "Hold" rating on the stock with an average target price of $33.94.
Dec 23, 2025 • The Globe and Mail NEUTRAL
Analysts’ Opinions Are Mixed on These Healthcare Stocks: Apellis Pharmaceuticals (APLS) and Argenx Se (ARGX)
This article presents mixed analyst opinions on two healthcare stocks: Apellis Pharmaceuticals (APLS) and Argenx Se (ARGX). While Apellis Pharmaceuticals received a "Hold" rating from Mizuho Securities, it holds a "Moderate Buy" consensus from analysts. Argenx Se maintains a "Strong Buy" consensus, with William Blair and J.P. Morgan both issuing "Buy" ratings and significant price targets.
Dec 22, 2025 • 富途牛牛 NEUTRAL
Mizuho Securities Maintains Apellis Pharmaceuticals(APLS.US) With Hold Rating
Mizuho Securities analyst Graig Suvannavejh has maintained a "hold" rating for Apellis Pharmaceuticals (APLS.US). The analyst has a 49.8% success rate and an average return of 15.8% over the past year, according to TipRanks data. The rating is for informational purposes and not an investment recommendation.
Dec 19, 2025 • MarketBeat NEUTRAL
Stifel Nicolaus Cuts Apellis Pharmaceuticals (NASDAQ:APLS) Price Target to $48.00
Stifel Nicolaus lowered its price target for Apellis Pharmaceuticals (NASDAQ:APLS) from $55.00 to $48.00, while maintaining a "buy" rating, indicating a potential upside of 93.22%. Despite a strong Q3 earnings report where Apellis exceeded revenue and EPS estimates, insider selling has occurred, and other analysts have varying ratings, leading to a consensus "Hold" rating with an average target price of $33.94. The company develops therapeutic compounds for autoimmune and inflammatory diseases, with its stock currently trading around $24.84.
Sentiment Snapshot

Average Sentiment Score:

0.154
50 articles with scored sentiment

Overall Sentiment:

Bullish

APLS Reported Earnings

Jul 31, 2025
Jun 30, 2025 (Pre market)
0.15 Surprise
  • Reported EPS: $-0.33
  • Estimate: $-0.48
  • Whisper:
  • Surprise %: 31.2%
May 07, 2025
Mar 31, 2025 (Pre market)
-0.2 Surprise
  • Reported EPS: $-0.74
  • Estimate: $-0.54
  • Whisper:
  • Surprise %: -37.0%
Feb 28, 2025
Dec 31, 2024 (Pre market)
0.11 Surprise
  • Reported EPS: $-0.29
  • Estimate: $-0.40
  • Whisper:
  • Surprise %: 27.8%
Nov 05, 2024
Sep 30, 2024 (Pre market)
-0.16 Surprise
  • Reported EPS: $-0.46
  • Estimate: $-0.30
  • Whisper:
  • Surprise %: -54.1%
Aug 01, 2024
Jun 30, 2024 (Pre market)
0.04 Surprise
  • Reported EPS: $-0.28
  • Estimate: $-0.32
  • Whisper:
  • Surprise %: 12.5%
May 07, 2024
Mar 31, 2024 (Pre market)
0.05 Surprise
  • Reported EPS: $-0.42
  • Estimate: $-0.47
  • Whisper:
  • Surprise %: 10.6%
Feb 27, 2024
Dec 31, 2023 (Pre market)
-0.04 Surprise
  • Reported EPS: $-0.73
  • Estimate: $-0.69
  • Whisper:
  • Surprise %: -5.8%
Nov 01, 2023
Sep 30, 2023 (Pre market)
-0.31 Surprise
  • Reported EPS: $-1.17
  • Estimate: $-0.86
  • Whisper:
  • Surprise %: -36.0%
Jul 31, 2023
Jun 30, 2023 (Pre market)
0.3 Surprise
  • Reported EPS: $-1.02
  • Estimate: $-1.32
  • Whisper:
  • Surprise %: 22.7%

Financials