AXSM Axsome Therapeutics Inc

$148.79

*Only the 1D chart reflects 15-min delayed quotes during market hours. Other timeframes update after market close.

Reporting for fiscal period ending
Expected on
Report Time: Unknown Release Time
The Whisper Number
Consensus Estimate:
Revenue Estimate:

Latest Earnings Insight

Axsome Therapeutics (AXSM) is poised for its upcoming earnings report on November 3, 2025, with a market cap of approximately $6.57 billion, reflecting investor confidence in its innovative pipeline. Despite the absence of recent news, the company's strategic focus on developing novel therapies for central nervous system disorders continues to capture market interest. Analysts anticipate flat earnings per share (EPS) at $0.00, aligning with the whisper number, while revenue is expected to reach $162.43 million. This revenue estimate underscores Axsome's potential to maintain its growth trajectory, driven by the successful commercialization of its key products. As the market awaits the earnings release, the alignment of the EPS estimate with the whisper number suggests that investors are cautiously optimistic about Axsome's ability to meet expectations, while any deviation in revenue could provide further insight into the company's operational momentum.

Updated On 1/6/2026

About Axsome Therapeutics Inc

Axsome Therapeutics, Inc., a biopharmaceutical company, is dedicated to developing new therapies for central nervous system (CNS) disorders in the United States. The company is headquartered in New York, New York.

Website: https://www.axsome.com

Sector
LIFE SCIENCES
Industry
PHARMACEUTICAL PREPARATIONS
Exchange
NASDAQ
Country
USA
Currency
USD
Fiscal Year End
December
CIK
1579428
Address
22 CORTLANDT STREET, 16TH FLOOR, NEW YORK, NY, US
Valuation
Market Cap
$5.09B
P/E Ratio
nan
PEG Ratio
0.00
Price to Book
89.35
Performance
EPS
$-5.99
Dividend Yield
Profit Margin
-74.50%
ROE
-231.60%
Technicals
50D MA
$118.95
200D MA
$97.81
52W High
$139.13
52W Low
$64.11
Fundamentals
Shares Outstanding
49M
Target Price
$177.35
Beta
0.88

AXSM EPS Estimates vs Actual

Estimated
Actual

AXSM News & Sentiment

Dec 30, 2025 • Stock Traders Daily NEUTRAL
Behavioral Patterns of AXSM and Institutional Flows
This article analyzes Axsome Therapeutics Inc. (NASDAQ: AXSM) focusing on near-term neutral sentiment amidst mid and long-term strength. It highlights resistance testing, an exceptional 37.5:1 risk-reward short setup, and offers three distinct AI-generated trading strategies. The strategies include position trading, momentum breakout, and risk hedging, each tailored for different risk profiles and holding periods, supported by multi-timeframe signal analysis.
Dec 23, 2025 • MarketBeat SOMEWHAT-BEARISH
Voya Investment Management LLC Decreases Stake in Axsome Therapeutics, Inc. $AXSM
Voya Investment Management LLC reduced its stake in Axsome Therapeutics, Inc. by 18.1% in the third quarter, selling 25,239 shares and holding 114,050 shares valued at approximately $13.85 million. The company reported a significant revenue increase but missed EPS expectations, remaining unprofitable with a negative return on equity. Several analysts maintain a "Moderate Buy" consensus rating with a price target of $179.88, despite recent insider selling activities.
Dec 19, 2025 • The Globe and Mail BULLISH
Axsome Therapeutics (AXSM) Gets a Buy from Jefferies
Jefferies maintained a Buy rating on Axsome Therapeutics (AXSM) with a price target of $200.00. This follows RBC Capital's Buy rating and contrasts with TR | OpenAI – 4o's Hold rating on the company. Axsome Therapeutics reported a quarterly revenue of $170.99 million and a GAAP net loss of $47.23 million for the quarter ending September 30.
Dec 19, 2025 • Investing.com BULLISH
Axsome Therapeutics stock hits all-time high at 152.98 USD
Axsome Therapeutics Inc. (AXSM) stock reached an all-time high of $152.98, marking a significant milestone driven by strong investor confidence and impressive growth. The company reported a 67.08% increase over the past year and a 73.74% year-to-date return, showcasing its successful strategies and innovations. Axsome also announced strong Q3 2025 revenues and strategic acquisitions in the epilepsy treatment space, reinforcing its growth trajectory in the biopharmaceutical sector.
Dec 15, 2025 • MarketBeat NEUTRAL
Castleark Management LLC Buys 19,250 Shares of Axsome Therapeutics, Inc. $AXSM
Castleark Management LLC significantly increased its stake in Axsome Therapeutics, purchasing an additional 19,250 shares in Q2 to bring its total to 38,040 shares valued at approximately $3.97 million. Despite this institutional buying, major insider selling by the CEO and COO has occurred, with insiders cumulatively disposing of 364,798 shares worth $47.53 million recently. Analysts maintain a "Moderate Buy" rating for Axsome with an average price target of $179.88, reflecting optimism despite the company missing EPS estimates and remaining unprofitable in its last earnings report.
Dec 14, 2025 • Simply Wall Street BULLISH
Will Stronger Results And Bullish Analyst Coverage Change Axsome Therapeutics' (AXSM) Risk‑Reward Narrative?
Axsome Therapeutics has seen renewed positive analyst coverage and improved quarterly results, with higher revenue and a narrower net loss. These developments suggest potential improvements in operational efficiency and sustained confidence in its central nervous system therapy portfolio. Investors are now evaluating how these changes will impact the company's investment narrative and future risk-reward profile, particularly regarding its path to profitability given ongoing heavy spending.
Sentiment Snapshot

Average Sentiment Score:

0.205
50 articles with scored sentiment

Overall Sentiment:

Bullish

AXSM Reported Earnings

Aug 04, 2025
Jun 30, 2025 (Pre market)
0.09 Surprise
  • Reported EPS: $-0.97
  • Estimate: $-1.06
  • Whisper:
  • Surprise %: 8.5%
May 05, 2025
Mar 31, 2025 (Pre market)
-0.01 Surprise
  • Reported EPS: $-1.22
  • Estimate: $-1.21
  • Whisper:
  • Surprise %: -0.5%
Feb 18, 2025
Dec 31, 2024 (Pre market)
-0.54 Surprise
  • Reported EPS: $-1.54
  • Estimate: $-1.00
  • Whisper:
  • Surprise %: -53.6%
Nov 12, 2024
Sep 30, 2024 (Pre market)
0.07 Surprise
  • Reported EPS: $-1.34
  • Estimate: $-1.41
  • Whisper:
  • Surprise %: 4.8%
Aug 05, 2024
Jun 30, 2024 (Pre market)
-0.34 Surprise
  • Reported EPS: $-1.67
  • Estimate: $-1.33
  • Whisper:
  • Surprise %: -25.6%
May 06, 2024
Mar 31, 2024 (Pre market)
-0.24 Surprise
  • Reported EPS: $-1.44
  • Estimate: $-1.20
  • Whisper:
  • Surprise %: -20.0%
Feb 20, 2024
Dec 31, 2023 (Pre market)
-0.91 Surprise
  • Reported EPS: $-2.08
  • Estimate: $-1.17
  • Whisper:
  • Surprise %: -77.8%
Nov 06, 2023
Sep 30, 2023 (Pre market)
-0.12 Surprise
  • Reported EPS: $-1.32
  • Estimate: $-1.20
  • Whisper:
  • Surprise %: -10.0%
Aug 07, 2023
Jun 30, 2023 (Pre market)
-0.32 Surprise
  • Reported EPS: $-1.54
  • Estimate: $-1.22
  • Whisper:
  • Surprise %: -26.2%

Financials