IONS Ionis Pharmaceuticals Inc

$42.69

*Only the 1D chart reflects 15-min delayed quotes during market hours. Other timeframes update after market close.

Reporting for fiscal period ending
Expected on
Report Time: Unknown Release Time
The Whisper Number
Consensus Estimate:
Revenue Estimate:

Latest Earnings Insight

Updated On 8/22/2025

About Ionis Pharmaceuticals Inc

Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapies in the United States. The company is headquartered in Carlsbad, California.

Website: https://www.ionis.com

Sector
LIFE SCIENCES
Industry
PHARMACEUTICAL PREPARATIONS
Exchange
NASDAQ
Country
USA
Currency
USD
Fiscal Year End
December
CIK
874015
Address
2855 GAZELLE COURT, CARLSBAD, CA, US
Valuation
Market Cap
$4.51B
P/E Ratio
nan
PEG Ratio
25.70
Price to Book
7.67
Performance
EPS
$-3.04
Dividend Yield
Profit Margin
-64.40%
ROE
-93.10%
Technicals
50D MA
$31.15
200D MA
$38.24
52W High
$52.34
52W Low
$23.95
Fundamentals
Shares Outstanding
159M
Target Price
$57.39
Beta
0.29

IONS EPS Estimates vs Actual

Estimated
Actual

IONS News & Sentiment

Aug 22, 2025 • Benzinga SOMEWHAT-BULLISH
What's Going On With Takeda Stock On Friday? - Takeda Pharmaceutical Co ( NYSE:TAK )
Dawnzera is priced at $57,462 per dose, with peak annual sales estimated at $509 million by 2032. Takeda's Takhzyro sales rose 3.7% to 55.1 billion yen in Q2 2025 despite rising competition. See the seasonal trading strategy that's beating the S&P 500 by 6X this year. Details here →
Aug 21, 2025 • Benzinga NEUTRAL
Why Is Ionis Pharma Stock Gaining Thursday? - Ionis Pharmaceuticals ( NASDAQ:IONS )
Dawnzera cut monthly HAE attacks by 81% vs placebo in Phase 3, with up to 87% reduction after second dose. Patients switching from Takhzyro or Orladeyo saw a 62% lower HAE attack rate with Dawnzera. See the 6X seasonal strategy set to target this fall's biggest opportunities. Details here →
Aug 21, 2025 • Benzinga SOMEWHAT-BULLISH
IONS Premarket Gains 2.4% After C-Suite Insider Sells $440K In Stock - Stifel Financial ( NYSE:SF ) , Ionis Pharmaceuticals ( NASDAQ:IONS )
Ionis Pharmaceuticals Inc. IONS closed regular trading at $42.81, up 0.78% for the day, before gaining an additional 2.38% in premarket trading to $43.83, according to Benzinga Pro data, following disclosure of insider trading activity by its chief scientific officer.
Jul 31, 2025 • Zacks Commentary SOMEWHAT-BULLISH
BioCryst Pharmaceuticals Before Q2 Earnings: How to Play the Stock
BCRX gears up for Q2 results with Orladeyo growth in focus, but 2025 EPS forecasts dip as investors eye pipeline progress.
Jul 31, 2025 • Motley Fool SOMEWHAT-BULLISH
Ionis ( IONS ) Q2 Revenue Soars 101%
Ionis Pharmaceuticals ( NASDAQ:IONS ) , a biotechnology company focused on RNA-targeted therapeutics, reported its second quarter 2025 earnings on July 30, 2025. The headline news was a substantial beat on both GAAP revenue and non-GAAP earnings compared to Wall Street estimates.
Jul 31, 2025 • Zacks Commentary NEUTRAL
Ionis Beats on Q2 Earnings & Sales, Stock Up 5% on Raised '25 Outlook
Ionis crushes Q2 estimates with EPS of $0.86 and sales of $452 million, lifting its 2025 revenue forecast and sending shares up 5%.
Sentiment Snapshot

Average Sentiment Score:

0.150
50 articles with scored sentiment

Overall Sentiment:

Bullish

IONS Reported Earnings

May 05, 2025
Mar 31, 2025 (Pre market)
0.09 Surprise
  • Reported EPS: $-0.92
  • Estimate: $-1.01
  • Whisper:
  • Surprise %: 8.5%
Feb 19, 2025
Dec 31, 2024 (Pre market)
0.41 Surprise
  • Reported EPS: $-0.43
  • Estimate: $-0.84
  • Whisper:
  • Surprise %: 49.0%
Nov 06, 2024
Sep 30, 2024 (Pre market)
0.21 Surprise
  • Reported EPS: $-0.95
  • Estimate: $-1.16
  • Whisper:
  • Surprise %: 18.1%
Aug 01, 2024
Jun 30, 2024 (Pre market)
0.47 Surprise
  • Reported EPS: $-0.45
  • Estimate: $-0.92
  • Whisper:
  • Surprise %: 51.1%
May 07, 2024
Mar 31, 2024 (Pre market)
0.07 Surprise
  • Reported EPS: $-0.98
  • Estimate: $-1.05
  • Whisper:
  • Surprise %: 6.7%
Feb 21, 2024
Dec 31, 2023 (Pre market)
0.77 Surprise
  • Reported EPS: $-0.06
  • Estimate: $-0.83
  • Whisper:
  • Surprise %: 92.8%
Nov 02, 2023
Sep 30, 2023 (Pre market)
0.01 Surprise
  • Reported EPS: $-1.03
  • Estimate: $-1.04
  • Whisper:
  • Surprise %: 1.0%
Aug 09, 2023
Jun 30, 2023 (Pre market)
0.3 Surprise
  • Reported EPS: $-0.60
  • Estimate: $-0.90
  • Whisper:
  • Surprise %: 33.3%
May 03, 2023
Mar 31, 2023 (Pre market)
0.04 Surprise
  • Reported EPS: $-0.87
  • Estimate: $-0.91
  • Whisper:
  • Surprise %: 4.4%

Financials