IONS Ionis Pharmaceuticals Inc

$76.09

*Only the 1D chart reflects 15-min delayed quotes during market hours. Other timeframes update after market close.

Reporting for fiscal period ending
Expected on
Report Time: Unknown Release Time
The Whisper Number
Consensus Estimate:
Revenue Estimate:

Latest Earnings Insight

Updated On 11/21/2025

About Ionis Pharmaceuticals Inc

Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapies in the United States. The company is headquartered in Carlsbad, California.

Website: https://www.ionis.com

Sector
LIFE SCIENCES
Industry
PHARMACEUTICAL PREPARATIONS
Exchange
NASDAQ
Country
USA
Currency
USD
Fiscal Year End
December
CIK
874015
Address
2855 GAZELLE COURT, CARLSBAD, CA, US
Valuation
Market Cap
$4.51B
P/E Ratio
nan
PEG Ratio
25.70
Price to Book
7.67
Performance
EPS
$-3.04
Dividend Yield
Profit Margin
-64.40%
ROE
-93.10%
Technicals
50D MA
$31.15
200D MA
$38.24
52W High
$52.34
52W Low
$23.95
Fundamentals
Shares Outstanding
159M
Target Price
$57.39
Beta
0.29

IONS EPS Estimates vs Actual

Estimated
Actual

IONS News & Sentiment

Nov 20, 2025 • GlobeNewswire SOMEWHAT-BULLISH
Biogen to Highlight New Lecanemab Data and Scientific Advances at the 18th Clinical Trials on Alzheimer's Disease Conference
CAMBRIDGE, Mass., Nov. 20, 2025 ( GLOBE NEWSWIRE ) -- Biogen Inc. ( Nasdaq: BIIB ) today announced upcoming scientific presentations at the 18th Clinical Trials on Alzheimer's Disease ( CTAD ) Conference, taking place December 1-4 in San Diego.
Nov 18, 2025 • GlobeNewswire SOMEWHAT-BULLISH
Akari Therapeutics Appoints Biotech Finance Leader, Kameel D. Farag as Interim Chief Financial Officer
More than 20 years of financial and operational leadership in biopharma, including $170M+ in capital raised, global commercialization experience, and a proven track record scaling companies from preclinical to clinical milestones More than 20 years of financial and operational leadership in ...
Nov 18, 2025 • Benzinga SOMEWHAT-BULLISH
Akari Therapeutics Appoints Biotech Finance Leader, Kameel D. Farag as Interim Chief Financial Officer - Akari Therapeutics ( NASDAQ:AKTX )
TAMPA and LONDON, Nov. 18, 2025 ( GLOBE NEWSWIRE ) -- Akari Therapeutics, Plc ( NASDAQ:AKTX ) , an oncology biotechnology company developing novel payloads for antibody drug conjugates ( ADCs ) , today announced the appointment of Kameel D. Farag as its Interim Chief Financial Officer who joined ...
Nov 17, 2025 • Benzinga NEUTRAL
High Dose Regimen of Nusinersen Receives Positive CHMP Opinion for the Treatment of Spinal Muscular Atrophy - Ionis Pharmaceuticals ( NASDAQ:IONS ) , Biogen ( NASDAQ:BIIB )
Positive CHMP opinion is based on data from the DEVOTE study which evaluated the high dose regimen of nusinersen in treatment-naive participants and those transitioning from the currently approved 12mg dose regimen1 Final European Commission decision expected in January 2026
Nov 14, 2025 • GlobeNewswire NEUTRAL
Biogen Completes Acquisition of Alcyone Therapeutics
CAMBRIDGE, Mass., Nov. 14, 2025 ( GLOBE NEWSWIRE ) -- Biogen Inc. ( Nasdaq: BIIB ) has completed the acquisition of Alcyone Therapeutics, a clinical-stage biotechnology company known for its innovative CNS therapy delivery solutions, such as the ThecaFlex DRx™ drug delivery system.
Nov 14, 2025 • Benzinga NEUTRAL
Biogen Completes Acquisition of Alcyone Therapeutics - Ionis Pharmaceuticals ( NASDAQ:IONS ) , Biogen ( NASDAQ:BIIB )
CAMBRIDGE, Mass., Nov. 14, 2025 ( GLOBE NEWSWIRE ) -- Biogen Inc. ( NASDAQ:BIIB ) has completed the acquisition of Alcyone Therapeutics, a clinical-stage biotechnology company known for its innovative CNS therapy delivery solutions, such as the ThecaFlex DRx™ drug delivery system.
Sentiment Snapshot

Average Sentiment Score:

0.166
50 articles with scored sentiment

Overall Sentiment:

Bullish

IONS Reported Earnings

Jul 30, 2025
Jun 30, 2025 (Pre market)
0.94 Surprise
  • Reported EPS: $0.70
  • Estimate: $-0.24
  • Whisper:
  • Surprise %: 391.7%
Apr 30, 2025
Mar 31, 2025 (Pre market)
0.09 Surprise
  • Reported EPS: $-0.92
  • Estimate: $-1.01
  • Whisper:
  • Surprise %: 8.5%
Feb 19, 2025
Dec 31, 2024 (Pre market)
0.41 Surprise
  • Reported EPS: $-0.43
  • Estimate: $-0.84
  • Whisper:
  • Surprise %: 49.0%
Nov 06, 2024
Sep 30, 2024 (Pre market)
0.21 Surprise
  • Reported EPS: $-0.95
  • Estimate: $-1.16
  • Whisper:
  • Surprise %: 18.1%
Aug 01, 2024
Jun 30, 2024 (Pre market)
0.47 Surprise
  • Reported EPS: $-0.45
  • Estimate: $-0.92
  • Whisper:
  • Surprise %: 51.1%
May 07, 2024
Mar 31, 2024 (Pre market)
0.07 Surprise
  • Reported EPS: $-0.98
  • Estimate: $-1.05
  • Whisper:
  • Surprise %: 6.7%
Feb 21, 2024
Dec 31, 2023 (Pre market)
0.77 Surprise
  • Reported EPS: $-0.06
  • Estimate: $-0.83
  • Whisper:
  • Surprise %: 92.8%
Nov 02, 2023
Sep 30, 2023 (Pre market)
0.01 Surprise
  • Reported EPS: $-1.03
  • Estimate: $-1.04
  • Whisper:
  • Surprise %: 1.0%
Aug 09, 2023
Jun 30, 2023 (Pre market)
0.3 Surprise
  • Reported EPS: $-0.60
  • Estimate: $-0.90
  • Whisper:
  • Surprise %: 33.3%

Financials