IONS Ionis Pharmaceuticals Inc

$69.02

*Only the 1D chart reflects 15-min delayed quotes during market hours. Other timeframes update after market close.

Reporting for fiscal period ending
Expected on
Report Time: Unknown Release Time
The Whisper Number
Consensus Estimate:
Revenue Estimate:

Latest Earnings Insight

Updated On 10/6/2025

About Ionis Pharmaceuticals Inc

Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapies in the United States. The company is headquartered in Carlsbad, California.

Website: https://www.ionis.com

Sector
LIFE SCIENCES
Industry
PHARMACEUTICAL PREPARATIONS
Exchange
NASDAQ
Country
USA
Currency
USD
Fiscal Year End
December
CIK
874015
Address
2855 GAZELLE COURT, CARLSBAD, CA, US
Valuation
Market Cap
$4.51B
P/E Ratio
nan
PEG Ratio
25.70
Price to Book
7.67
Performance
EPS
$-3.04
Dividend Yield
Profit Margin
-64.40%
ROE
-93.10%
Technicals
50D MA
$31.15
200D MA
$38.24
52W High
$52.34
52W Low
$23.95
Fundamentals
Shares Outstanding
159M
Target Price
$57.39
Beta
0.29

IONS EPS Estimates vs Actual

Estimated
Actual

IONS News & Sentiment

Sep 24, 2025 • Zacks Commentary SOMEWHAT-BULLISH
BIIB's sNDA for Higher Dose of SMA Drug Spinraza Gets FDA's CRL
FDA issues CRL to Biogen's regulatory filing seeking approval for a higher dose of SMA drug, Spinraza. The company plans prompt resubmission.
Sep 23, 2025 • GlobeNewswire NEUTRAL
Biogen Provides Regulatory Update on High Dose Regimen of Nusinersen
CAMBRIDGE, Mass., Sept. 23, 2025 ( GLOBE NEWSWIRE ) -- Biogen Inc. ( Nasdaq: BIIB ) today announced that the U.S. Food and Drug Administration ( FDA ) issued a Complete Response Letter ( CRL ) for the Company's supplemental New Drug Application ( sNDA ) for the high dose regimen of nusinersen for ...
Sep 23, 2025 • Benzinga NEUTRAL
Biogen Provides Regulatory Update on High Dose Regimen of Nusinersen - Ionis Pharmaceuticals ( NASDAQ:IONS ) , Biogen ( NASDAQ:BIIB )
CAMBRIDGE, Mass., Sept. 23, 2025 ( GLOBE NEWSWIRE ) -- Biogen Inc. BIIB today announced that the U.S. Food and Drug Administration ( FDA ) issued a Complete Response Letter ( CRL ) for the Company's supplemental New Drug Application ( sNDA ) for the high dose regimen of nusinersen for the ...
Sep 23, 2025 • Zacks Commentary SOMEWHAT-BULLISH
IONS' Rare Neurological Disease Drug Meets Late-Stage Study Goal
Ionis' zilganersen hits its phase III goal in Alexander disease, paving the way for a potential FDA filing in early 2026.
Sep 22, 2025 • Benzinga NEUTRAL
Ionis Pharmaceuticals Reveals 'Unprecedented Results' From Rare Neurological Disease Trial - Ionis Pharmaceuticals ( NASDAQ:IONS )
Ionis Pharmaceuticals, Inc. IONS released topline results on Monday from the pivotal study of zilganersen in children and adults living with Alexander disease ( AxD ) , a rare, progressive, and often fatal neurological condition.
Sep 18, 2025 • GlobeNewswire NEUTRAL
Biogen to Acquire Alcyone Therapeutics, Expanding Drug Delivery Solution Portfolio for Key Product and Pipeline Candidates
CAMBRIDGE, Mass., Sept. 18, 2025 ( GLOBE NEWSWIRE ) -- Biogen Inc. ( Nasdaq: BIIB ) announced the company has entered into a definitive agreement to acquire Massachusetts-based Alcyone Therapeutics. As part of an existing partnership with Alcyone Therapeutics, the companies are advancing ...
Sentiment Snapshot

Average Sentiment Score:

0.132
50 articles with scored sentiment

Overall Sentiment:

Neutral

IONS Reported Earnings

May 05, 2025
Mar 31, 2025 (Pre market)
0.09 Surprise
  • Reported EPS: $-0.92
  • Estimate: $-1.01
  • Whisper:
  • Surprise %: 8.5%
Feb 19, 2025
Dec 31, 2024 (Pre market)
0.41 Surprise
  • Reported EPS: $-0.43
  • Estimate: $-0.84
  • Whisper:
  • Surprise %: 49.0%
Nov 06, 2024
Sep 30, 2024 (Pre market)
0.21 Surprise
  • Reported EPS: $-0.95
  • Estimate: $-1.16
  • Whisper:
  • Surprise %: 18.1%
Aug 01, 2024
Jun 30, 2024 (Pre market)
0.47 Surprise
  • Reported EPS: $-0.45
  • Estimate: $-0.92
  • Whisper:
  • Surprise %: 51.1%
May 07, 2024
Mar 31, 2024 (Pre market)
0.07 Surprise
  • Reported EPS: $-0.98
  • Estimate: $-1.05
  • Whisper:
  • Surprise %: 6.7%
Feb 21, 2024
Dec 31, 2023 (Pre market)
0.77 Surprise
  • Reported EPS: $-0.06
  • Estimate: $-0.83
  • Whisper:
  • Surprise %: 92.8%
Nov 02, 2023
Sep 30, 2023 (Pre market)
0.01 Surprise
  • Reported EPS: $-1.03
  • Estimate: $-1.04
  • Whisper:
  • Surprise %: 1.0%
Aug 09, 2023
Jun 30, 2023 (Pre market)
0.3 Surprise
  • Reported EPS: $-0.60
  • Estimate: $-0.90
  • Whisper:
  • Surprise %: 33.3%
May 03, 2023
Mar 31, 2023 (Pre market)
0.04 Surprise
  • Reported EPS: $-0.87
  • Estimate: $-0.91
  • Whisper:
  • Surprise %: 4.4%

Financials