VRTX Vertex Pharmaceuticals Inc

$453.74

*Only the 1D chart reflects 15-min delayed quotes during market hours. Other timeframes update after market close.

Reporting for fiscal period ending
Expected on
Report Time: Unknown Release Time
The Whisper Number
Consensus Estimate:
Revenue Estimate:

Latest Earnings Insight

Vertex Pharmaceuticals is set to announce its third-quarter earnings on November 3, 2025, and investors are keenly watching for signs of continued growth following a robust first half of the year. The company, renowned for its leadership in rare disease therapeutics, particularly cystic fibrosis, has demonstrated a strong financial trajectory with a 12% revenue increase in Q2 2025. Analysts are forecasting an EPS of $4.57, slightly above the whisper number of $4.40, indicating a positive sentiment despite recent stock volatility. With a market cap of over $107 billion, Vertex's strategic expansion into new therapies like CASGEVY and JOURNAVX, alongside its promising Type 1 Diabetes program, underscores its potential for sustained revenue growth. The revenue estimate for this quarter stands at $3.06 billion, reflecting expectations of continued momentum from its innovative pipeline and strong commercialization efforts. As Vertex navigates the complexities of the biotech landscape, its ability to translate scientific breakthroughs into financial success remains a focal point for investors.

Updated On 1/6/2026

About Vertex Pharmaceuticals Inc

Vertex Pharmaceuticals, Inc. is an American biopharmaceutical company based in Boston, Massachusetts.

Website: https://www.vrtx.com

Sector
LIFE SCIENCES
Industry
PHARMACEUTICAL PREPARATIONS
Exchange
NASDAQ
Country
USA
Currency
USD
Fiscal Year End
December
CIK
875320
Address
50 NORTHERN AVENUE, BOSTON, MA, US
Valuation
Market Cap
$125.74B
P/E Ratio
nan
PEG Ratio
1.34
Price to Book
7.66
Performance
EPS
$-2.10
Dividend Yield
Profit Margin
-4.86%
ROE
-3.15%
Technicals
50D MA
$486.22
200D MA
$470.93
52W High
$519.88
52W Low
$377.85
Fundamentals
Shares Outstanding
257M
Target Price
$498.43
Beta
0.51

VRTX EPS Estimates vs Actual

Estimated
Actual

VRTX News & Sentiment

Dec 31, 2025 • MarketBeat SOMEWHAT-BULLISH
25,734 Shares in Vertex Pharmaceuticals Incorporated $VRTX Bought by Generate Investment Management Ltd
Generate Investment Management Ltd recently acquired a new stake of 25,734 shares, valued at approximately $10.08 million, in Vertex Pharmaceuticals Incorporated during the third quarter. This purchase contributed to institutional investors owning 90.96% of the company's stock, despite significant insider selling in the last quarter. Vertex Pharmaceuticals has an average "Moderate Buy" rating and a consensus price target of $502.05 from analysts.
Dec 31, 2025 • MarketBeat SOMEWHAT-BULLISH
Ethic Inc. Has $5.47 Million Stock Position in Vertex Pharmaceuticals Incorporated $VRTX
Ethic Inc. increased its stake in Vertex Pharmaceuticals (NASDAQ:VRTX) by 21.5% in the third quarter, bringing its holding to 13,971 shares valued at approximately $5.47 million. Despite institutional ownership reaching 90.96%, significant insider selling has occurred, with insiders offloading 151,073 shares worth $67.33 million in the past 90 days, reducing their total ownership to 0.20%. Vertex Pharmaceuticals exceeded Q3 earnings expectations with $4.80 EPS and revenue of $3.08 billion, prompting analysts to maintain a "Moderate Buy" rating with a consensus price target of $502.05.
Dec 30, 2025 • ts2.tech SOMEWHAT-BEARISH
Rhythm Pharmaceuticals (RYTM) stock falls today as biotech weakens; FDA decision stays in focus
Rhythm Pharmaceuticals (RYTM) shares dropped today as the biotech sector weakened, with major biotech ETFs down over 1%. Investors are keenly awaiting the FDA's decision on a label expansion for Rhythm's obesity drug, Imcivree, for acquired hypothalamic obesity, with a new review deadline set for March 20, 2026. The company also faces competition in the Prader-Willi syndrome landscape and is preparing for Phase 3 trials and future updates.
Dec 30, 2025 • Finviz SOMEWHAT-BULLISH
2 Growth Stocks to Buy For 2026 and Beyond
This article recommends Vertex Pharmaceuticals (NASDAQ: VRTX) and DexCom (NASDAQ: DXCM) as two growth stocks to consider for 2026 and beyond. Vertex faces setbacks but has promising pipeline candidates and recent product launches like Journavx, while DexCom, a leader in continuous glucose monitoring (CGM), is expanding its market despite some product recalls and concerns about new diabetes treatments. Both companies are positioned for long-term growth through new product launches and market expansion.
Dec 30, 2025 • The Globe and Mail SOMEWHAT-BULLISH
Analysts Are Bullish on These Healthcare Stocks: Vertex Pharmaceuticals (VRTX), Edgewise Therapeutics (EWTX)
Two healthcare stocks, Vertex Pharmaceuticals (VRTX) and Edgewise Therapeutics (EWTX), have received bullish sentiments from analysts. Leerink Partners reiterated a Buy rating for Vertex Pharmaceuticals with a $525.00 price target, and maintains its Strong Buy consensus. Edgewise Therapeutics also received a Buy rating from Leerink Partners, with an average price target that suggests a significant upside, supported by a Strong Buy consensus.
Dec 30, 2025 • Yahoo Finance BULLISH
Vertex Pharmaceuticals price target raised to $525 from $456 at Leerink
Leerink has increased its price target for Vertex Pharmaceuticals (VRTX) to $525 from $456, maintaining an Outperform rating. This adjustment is based on an increased terminal growth assumption from 1% to 2% and an optimistic view of the company's revenue and pipeline prospects. The firm does note that it projects higher investment spending growth compared to consensus models.
Sentiment Snapshot

Average Sentiment Score:

0.254
50 articles with scored sentiment

Overall Sentiment:

Bullish

VRTX Reported Earnings

Aug 04, 2025
Jun 30, 2025 (Post market)
0.27 Surprise
  • Reported EPS: $4.52
  • Estimate: $4.25
  • Whisper:
  • Surprise %: 6.3%
May 05, 2025
Mar 31, 2025 (Post market)
-0.23 Surprise
  • Reported EPS: $4.06
  • Estimate: $4.29
  • Whisper:
  • Surprise %: -5.4%
Feb 10, 2025
Dec 31, 2024 (Post market)
-0.04 Surprise
  • Reported EPS: $3.98
  • Estimate: $4.02
  • Whisper:
  • Surprise %: -1.0%
Nov 04, 2024
Sep 30, 2024 (Post market)
0.25 Surprise
  • Reported EPS: $4.38
  • Estimate: $4.13
  • Whisper:
  • Surprise %: 6.0%
Aug 01, 2024
Jun 30, 2024 (Post market)
-15.77 Surprise
  • Reported EPS: $-12.83
  • Estimate: $2.94
  • Whisper:
  • Surprise %: -536.4%
May 06, 2024
Mar 31, 2024 (Post market)
0.7 Surprise
  • Reported EPS: $4.76
  • Estimate: $4.06
  • Whisper:
  • Surprise %: 17.2%
Feb 05, 2024
Dec 31, 2023 (Post market)
0.1 Surprise
  • Reported EPS: $4.20
  • Estimate: $4.10
  • Whisper:
  • Surprise %: 2.4%
Nov 06, 2023
Sep 30, 2023 (Post market)
0.11 Surprise
  • Reported EPS: $4.08
  • Estimate: $3.97
  • Whisper:
  • Surprise %: 2.8%
Aug 01, 2023
Jun 30, 2023 (Post market)
0.01 Surprise
  • Reported EPS: $3.89
  • Estimate: $3.88
  • Whisper:
  • Surprise %: 0.3%

Financials